Predictors of mortality related to Covid-19

Abstract

Introduction: The new 2019 coronavirus has spread rapidly around the world, creating a pandemic. Since the beginning of the pandemic, 6.012.035 patients have died. The objective of this study is to identify clinical and biological parameters associated with high mortality in patients with COVID-19 pneumonia. Material and methods: We report a retrospective study carried out in a Covid department of the Mohamed VI University Hospital of Marrakech between 20 October and 20 December 2021. Patients were divided into 2 groups: a survivor group and a decedent group. Results: We collected 103 cases during this period. A male predominance was noted in 55.3% of cases. The group of deceased included 9 cases (8.7%) while the group of survivors contained 94 cases (91.2%). The average age of the patients in the survivor group was 44.6 years, while it was higher in the deceased group (60.6 years). We noted that the deceased patients had more arterial hypertension (55.6% vs. 10.6%) and heart disease (66.7% vs. 0%) than the survivors, and diabetes was more common in the deceased (77.8% vs. 12.8%). Clinical signs were more severe in the decedents. Biological tests showed lymphopenia in 88.9% of the deceased group. Cardiac troponins were also higher in the deceased group with a mean value of 172.7ng/l. Conclusion: Through our study, we identified four predictors of mortality: age ≥ 65 years, presence of comorbidities, lymphopenia and elevated cardiac troponins.