Abstract

Tuberculosis (TB) and human immunodeficiency virus (HIV) co-infection remain a major global and national health problem that requires substantial action to achieve the Sustainable Development Goals (SDG) and the END-TB strategies..

Highlights

  • Tuberculosis (TB) and human immunodeficiency virus (HIV) coinfection in the human body potentiate each other by weakening the immune system and causing death, if untreated

  • A retrospective hospital follow-up study was conducted in two zones of the Tigray Region (Mekelle and Southern), which is located in the northern part of Ethiopia by reviewing 10 years (20082018) medical records of children co-infected with TB and HIV in 2019

  • All children infected with TB and HIV co-infected under 15 years of age who received follow-up care from January 1 / 2008 to December 30/2018 in the ant-retroviral treatment (ART) clinic at public general hospitals of the Mekelle and southern zone of the Tigray region, North Ethiopia

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Summary

Introduction

Tuberculosis (TB) and human immunodeficiency virus (HIV) coinfection in the human body potentiate each other by weakening the immune system and causing death, if untreated. Tuberculosis is a major cause of morbidity and mortality in children infected with the human immunodeficiency virus. Tuberculosis (TB) and human immunodeficiency virus (HIV) co-infection remain a major global and national health problem that requires substantial action to achieve the Sustainable Development Goals (SDG) and the END-TB strategies [1]. Both TB and HIV are the leading causes of death from infectious diseases worldwide [2]. More than 1 in 5 TB and HIV coinfected individuals were died [10], but this huge problem was not known in children

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