Abstract
Aim. To evaluate the rate and reveal the predictors of long term adverse cardiovascular events after scheduled percutaneous coronary interventions (PCI). Material and methods . The rate of combination endpoint (МАССЕ — Major Adverse Cardiac and Cerebrovascular Events) was assessed in 151 patient in 6 years after selective PCI by medical data analysis and phone based interview. Results. In 6 years after scheduled PCI the mortality from cardiovascular events was in 10,6% patients, acute coronary syndrome developed in 34,4%, stroke in 6,6%. In general MACCE were noted in 40,4%. The predictors of MACCE in long term period were chronic kidney disease, contrast-induced kidney damage, baseline C-reactive protein >5,5 mg/mL. Restenoses of the previously placed stents increased the risk of MACCE 8,09 times, chronic obstructive pulmonary disease — 3,4 times, atrial fibrillation — 2,84 times, heredity by cardiovascular diseases — 2,94 times, and the very high risk of contrast-induced nephropathy (≥11 points by Mehran) — 2,15 times. Conclusion. Assessment for the predictors of long term adverse cardiovascular events in patients after scheduled PCI makes it, based on simple clinical characteristics, to select the groups of patients with residual risk that require on-time application of more active secondary prevention strategies with further follow-up.
Highlights
ConclusionAssessment for the predictors of long term adverse cardiovascular events in patients after scheduled PCI makes it, based on simple clinical characteristics, to select the groups of patients with residual risk that require on-time application of more active secondary prevention strategies with further follow-up.
ДИ — доверительный интервал, ИБС — ишемическая болезнь сердца, КИН — контраст-индуцированная нефропатия, КИ-ОПП — контраст-индуцированное острое повреждение почек, ОКС — острый коронарный синдром, ОНМК — острое нарушение мозгового кровообращения, ОШ — отношение шансов, СЛП — стенты с лекарственным покрытием, СРБ — С-реактивный белок, ССЗ — сердечно-сосудистые заболевания, ФП — фибрилляция предсердий, ХБП — хроническая болезнь почек, ХОБЛ — хроническая обструктивная болезнь легких, ЧКВ — чрескожное коронарное вмешательство, AUC — Area Under the Curve, MACCE — Major Adverse Cardiac and Cerebrovascular Events
Эндоваскулярные вмешательства на коронарных артерияхОптимальная вторичная профилактика атеросклероза была определена уже несколько лет назад.
Summary
Assessment for the predictors of long term adverse cardiovascular events in patients after scheduled PCI makes it, based on simple clinical characteristics, to select the groups of patients with residual risk that require on-time application of more active secondary prevention strategies with further follow-up. ДИ — доверительный интервал, ИБС — ишемическая болезнь сердца, КИН — контраст-индуцированная нефропатия, КИ-ОПП — контраст-индуцированное острое повреждение почек, ОКС — острый коронарный синдром, ОНМК — острое нарушение мозгового кровообращения, ОШ — отношение шансов, СЛП — стенты с лекарственным покрытием, СРБ — С-реактивный белок, ССЗ — сердечно-сосудистые заболевания, ФП — фибрилляция предсердий, ХБП — хроническая болезнь почек, ХОБЛ — хроническая обструктивная болезнь легких, ЧКВ — чрескожное коронарное вмешательство, AUC — Area Under the Curve, MACCE — Major Adverse Cardiac and Cerebrovascular Events
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