Abstract
640 Echocardiographically detected left ventricular hypertophy (LVH) is a powerful and independent predictor of cardiovascular events. Resting blood pressure (BP) is weakly associated with LVH, while a stronger association has been reported between LVH and exercise BP in men. However, it is not known if this relationship exists in women. We sought to determine predictors of left ventricular mass (LV mass) in normotensive (n=194;age=51±10) and hypertensive (n=115; age=57±8) women. All women were free of heart disease and antihypertensive medication. LVH (LVM Index ≥ 110) was present in 15% of the normotensive and 71% of the hypertensive women. Significant differences (p<0.05) between those with and without hypertension were also noted in age, resting BP, BMI and LV mass index. Multiple regression analysis with 15 selected independent variables, including resting systolic BP (RSBP), 6-minute exercise systolic BP (SBPII) and exercise time to exhaustion (ETE), revealed the following variables as the strongest predictors of LV mass: (Table)TableThus, SBP at 6 minutes of exercise is the strongest predictor of LV mass in normotensive and hypertensive.
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