Abstract

Despite the importance of early detection to signal lifesaving treatment initiation for HIV+ infants, early infant diagnosis (EID) services have received considerably less attention than other aspects of prevention of mother to child transmission care. This study draws on baseline data from an on-going cluster randomized study of an intervention to improve EID services at six government hospitals across Kenya. Two logistic regressions examined potential predictors of “on time” (infant ≤6 weeks of age) vs. “late” (≥7 weeks) and “on time” versus “very late” (≥12 weeks) EID engagement among 756 mother-infant pairs. A quarter of the infants failed to get “on time” testing. Predictors of “on time” testing included being informed about EID by providers when pregnant, perceiving less HIV stigma, and mother’s level of education. Predictors of “very late” testing (≥12 weeks of age) included not being informed about EID by providers when pregnant and living farther from services. Findings highlight the importance of ensuring that health care providers actively and repeatedly inform HIV+ mothers of the availability of EID services, reduce stigma by frequently communicating judgment free support, and assisting mothers in early planning for accessing EID services. Extra care should be focused on engaging mothers with less formal education who are at increased risk for seeking “late” EID testing. This study offers clear targets for improving services so that all HIV-exposed infants can be properly engaged in EID services, thus increasing the potential for the best possible outcomes for this vulnerable population.

Highlights

  • Findings highlight the importance of ensuring that health care providers actively and repeatedly inform HIV? mothers of the availability of early infant diagnosis (EID) services, reduce stigma by frequently communicating judgment free support, and assisting mothers in early planning for accessing EID services

  • Extra care should be focused on engaging mothers with less formal education who are at increased risk for seeking ‘‘late’’ EID testing

  • Infant diagnosis (EID; infant B6 weeks of age) of HIV infection that facilitates prompt treatment of HIV? infants is a critical component of prevention of mother-tochild transmission (PMTCT) efforts

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Summary

Introduction

Infant diagnosis (EID; infant B6 weeks of age) of HIV infection that facilitates prompt treatment of HIV? infants is a critical component of prevention of mother-tochild transmission (PMTCT) efforts. Infant diagnosis (EID; infant B6 weeks of age) of HIV infection that facilitates prompt treatment of HIV? In 2008 the Children with HIV Early ART (CHER) study provided evidence that early antiretroviral therapy (ART) initiation (before 12 weeks) reduced mortality by 76 % and slowed the AIDS Behav (2016) 20:2141–2150 progression of HIV by 75 % by improving long-term viral suppression and weight for age scores [3]. These findings prompted new World Health Organization (WHO) guidelines to treat all HIV? EID provides reassurance to the mothers of infants who remain HIV negative [10] which has been associated with improved infant bonding [11]

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