Predictors of Functional Changes in Italian Nursing Home Residents: The U.L.I.S.S.E. Study

Abstract

ObjectivesTo identify independent predictors of the risk of functional decline in older nursing home (NH) residents. DesignA longitudinal observational study. SettingThirty-one NHs participating in the U.L.I.S.S.E. project, distributed throughout Italy. ParticipantsAll older (≥65 years) long-term NH residents without complete disability and with at least one follow-up evaluation during the 12-month study period (n = 1263). MeasurementsAll participants underwent a standardized comprehensive evaluation using the Italian version of the Minimum Data Set for NHs. The activities of daily living (ADLs) Long-Form scale was used to evaluate functional status. Facility characteristics were collected using an ad hoc designed questionnaire. ResultsOf the NH residents, 40.4% experienced a decline in the ADL during the follow-up. The mixed effect logistic regression model showed that depression (odds ratio [OR] 1.45, confidence interval [CI] 1.16–1.81, P = .005) and the use of antipsychotics (OR 1.30, CI 1.06–1.60, P = .016) were associated with a higher probability of ADL decline, whereas the presence of a geriatrician (OR 0.60, CI 0.41–0.88, P = .015) and a higher than median hour per resident per week of nursing care (OR 0.55, CI 0.37–0.80, P = .006) were associated with a lower risk. ConclusionsOur findings suggest that preventing functional decline in NH residents might be possible by optimizing the management of depression and by reducing the current high prescription rate of antipsychotics. Moreover, the presence of a geriatrician, associated with an adequate amount of nursing care, seem to be important facilities characteristics to achieve this goal. These findings should be tested in large-scale pragmatic clinical trials.