Abstract

Little is known regarding the risk of recurrence of Clostridium difficile infection (CDI) in children. In a 9-year cohort, 12% of hospitalized children with CDI had recurrent disease. Receipt of concomitant antibiotics and community-associated CDI were independently associated with recurrent disease in children hospitalized with CDI. Antibiotics administered for reasons other than treatment of CDI should be discontinued whenever possible.

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