Abstract

Mechanisms underlying the manifestation of relatives' expressed emotion (EE) in the early stages of psychosis are still not properly understood. The present study aimed to examine whether relatives' psychological distress and subjective appraisals of the illness predicted EE dimensions over-and-above patients' poor clinical and functional status. Baseline patient-related variables and relatives attributes comprising criticism, emotional over-involvement (EOI), psychological distress, and illness attributions were assessed in 91 early psychosis patients and their respective relatives. Relatives were reassessed regarding EE dimensions at a 6-month follow-up. Relatives' psychological distress and illness attributions predicted criticism and EOI over-and-above patients' illness characteristics at both time points. Relatives' increased levels of anxiety, attributions of blame toward the patients, an emotional negative representation about the disorder, and decreased levels of self-blame attributions predicted EE-criticism at baseline. Relatives' anxiety and negative emotional representation of the disorder were the only significant predictors of EE-criticism at follow-up, whereas anxiety, attributions of control by the relative and an emotional negative representation about the disorder predicted EE-EOI both at baseline and follow-up assessments. Understanding the components that comprise and maintain EE attitudes should guide early psychosis caregivers in family interventions, enhancing proper management of psychological distress and reduction of negative appraisals about the illness. The prevention of high-EE attitudes over time in a sensitive period such as early psychosis might be critical in shaping the health of caregivers and the outcome of the affected relatives.

Highlights

  • Epidemiological research indicates that psychosocial factors impact the risk, progression and outcome of psychosis liability

  • Peer Review History: PLOS recognizes the benefits of transparency in the peer review process; we enable the publication of all of the content of peer review and author responses alongside final, published articles

  • Ninety-one early psychosis patients (55 at-risk mental state (ARMS) and 36 first-episode psychosis (FEP)) and their respective relatives were initially recruited in the present study

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Summary

Introduction

Epidemiological research indicates that psychosocial factors impact the risk, progression and outcome of psychosis liability. In the context of microenvironmental factors, one of the most significant factors in psychosocial research in psychosis has been expressed emotion (EE) [3], a measure of the family environment used to describe relatives’ attitudes toward an ill family member. High-EE attitudes, criticism and emotional over-involvement (EOI), are considered the strongest psychosocial predictors of relapse in schizophrenia [4]. Given the heightened stresssensitivity associated to psychosis liability [5], the impact of high negative emotionality and distress in the family environment appears relevant. EE is best regarded as the product of a negative dynamic interaction between patients and their families that can play a central role in the course of the patient’s disorder [6,7]

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