Abstract

symptoms, significant ECG changes, and/or rise in CK or troponin-I >3× upper limit of normal [or above baseline values in acute coronary syndromes (ACS)], and distinct fromthe indexevent) in14,584 consecutivePCIprocedures from April 2004 to September 2009. Results: Patients with PPMI (n= 184; 1.3%) compared to those without PPMI (n= 14,400) were older (67± 13 vs. 64± 12 years), had lower left ventricular ejection fraction (LVEF) (49± 14 vs. 53± 12%), and greater incidence of pre-existing heart failure and chronic lung disease (all p 70% of models) and chronic lung disease (predictive in >50% of models) increased the ROC to 90.7%; H-LÝ=Ý1.09 (pÝ=Ý0.78) and 91.6%; H-LÝ=Ý0.78 (pÝ=Ý0.94), respectively. Conclusion: CS, eGFR, OHCA and EF independently predicted 30-day mortality in unselected PCI cases with excellent statistical discrimination and calibration. This validated, simple clinical risk model may be useful in risk assessment prior to PCI. represent a high-risk cohort with considerably higher 30-day mortality, suggesting increased vigilance postprocedure is warranted. doi:10.1016/j.hlc.2011.05.354

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