Abstract

Clinically significant predictors of change in an intervention for the prevention of depression. One of the limitations of research in indicated prevention of depression is that few works have analyzed the clinical significance of the effects of the interventions. In this study, 170 non-professional caregivers with depressive symptoms were randomized to a cognitive-behavioral intervention group (n = 88) or to a usual-care control group (n = 82). The intervention was implemented in five weekly 90-minute sessions in groups of approximately five participants by trained psychologists. At postreatment, there was a significantly higher percentage of caregivers who achieved a clinically significant change in the intervention group compared to the control group (62.5% vs. 15.9%; x 2 (1, N = 170) = 38.48, p < .001). This was maintained until 12-month follow-up, when 81.8% of the intervention group obtained a clinically significant change compared to 17.1% in the control group (x 2 (1, N = 170) = 71.18, p < .001). The variables that predicted clinical change for the intervention group at postreatment were to be devoted to domestic work and older age of the care recipient. No predictors were found for the 12-month follow-up.

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