Abstract
Introduction: Wide spectrum of clinical features of COVID-19 was seen from mild to severe. This is very important to determine the severity of disease, early management of severe disorder may increase the chance of survival.
 Methods: This cross sectional study perform on 150 patients with mean age of 53 years that refer to from 21 February to 19 April 2020.
 Result: The most comorbidity disease HTN, DM and IHD with prevalence of 26.2%, 20%, 11.3% which had higher severity of lung disease. There was a significant relationship between age, lymphopenia, CRP, IHD, DM, shortness of breath and body pain with the severity of lung injury, shortness of breath had higher severity of lung injury but myalgia had a lower severity rather than the others. level of the LDH was associated with chest CT scan score and so severe disease Further results showed that the mean±SD of LDH in 3 CT group were 576.30±214.82, 641.89± 277.07, 919.92± 382.14 in CT score less than 20, 20-50 and more than 50 respectively (P=0.002).
 According this study there was significant relationship between age, BMI, CRP, shortness of breath and fever with blood oxygen saturation. Further results showed that the correlation between LDH and oxygen saturation was r=-0.31 (p=0.002)
Highlights
Wide spectrum of clinical features of COVID-19 was seen from mild to severe
There was a significant relationship between age, lymphopenia, CRP, IHD, DM, shortness of breath and body pain with the severity of lung injury, shortness of breath had higher severity of lung injury but myalgia had a lower severity rather than the others. level of the LDH was associated with chest CT scan score and so severe disease
The results showed that people with shortness of breath had a higher severity of lung injury than others, but people with myalgia had a lower severity of lung injury rather than others patients
Summary
Wide spectrum of clinical features of COVID-19 was seen from mild to severe. This is very important to determine the severity of disease, early management of severe disorder may increase the chance of survival. We attempted to answer some questions through a retrospective case-control study, where clinical characteristics of patients with moderate to severe COVID-19 evaluated for determining some essential factors affecting the susceptibility and disease severity of Covid-19 disease, resulting in identifying high-risk groups. The present study assessed the clinical and laboratory features and outcomes in patients with moderate to severe COVID-19 disease, to explore the risk factors affecting the susceptibility and disease severity
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