Predictive Values of Component-Specific IgE for the Outcome of Peanut and Hazelnut Food Challenges in Children

Abstract

K Beyer, L Grabenhenrich, M Hartl. Allergy. 2015;70(1):90–98 To prospectively analyze the value of peanut and hazelnut component-specific immunoglobulin (Ig)E testing in the diagnosis of peanut and hazelnut allergies. Infants and children who were clinically suspected to have allergy to peanut or hazelnut in various hospitals in Germany. Two hundred and ten patients underwent oral food challenge with peanut and 143 with hazelnut. Oral food challenges were done with roasted peanuts or raw hazelnuts with a cumulative dose of 4443 mg of protein. Specific IgE to peanut, hazelnut, and their components (Ara h 1, Ara h 2, Ara h 3, and Ara h 8; Cor a 1, Cor a 8, Cor a …