Abstract
Objective To investigate the predictive value of acute physiology and chronic health score (APCHE Ⅱ) scoring system on the patients with acute coronary syndrome (ACS), and to demonstrate whether the predictive value combined with TIMI risk score impact on prognosis. Methods We calculated APACHE Ⅱ, TIMI risk score and total score of these two for 198 patients with acute coronary syndrome (ACS) in CCU, and compared the discriminative power of the three scores by the area under the receiver operating characteristic curve (AUROCC). Results The APACHE Ⅱ scores of survival group (9.42±3.38) and death group (14.77±3.27) were statistically significant (t=-8.018, P 0.05); for the total ACS, the score of APACHE Ⅱ was (10.23±3.86) and predicted mortality 11.62% (23/198) and actually mortality 15.15%(30/198) (χ2=29.892, P<0.01). The ROC curve area of 3 score methods had been compared and found out TIMI had the biggest ROC curve area and the best predicted livability and mortality. Conclusions APACHE Ⅱ score can not predict mortality satisfactorily in patients with ACS well, and the method of APACHE Ⅱ combined with TIMI risk score is not better than TIMI risk score showed in the study. The TIMI risk score is a quick, convenient and effective method to evaluate patients with ACS. Key words: Acute coronary syndrome; Acute physiology and chronic health score; TIMI risk score
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