Predictive role of neutrophil-to-platelet ratio in futile recanalization of patients after endovascular therapy.

Abstract

Aim: To explore the association between the neutrophil-to-platelet ratio (NPR) and futile recanalization (FR) in patients with acute ischemic strokedue to large vascular occlusions after endovascular therapy (EVT). Methods: FR after EVT was defined as a poor 90-day prognosis (modified Rankin scale [mRS] score ≥3) despite successful reperfusion (modified thrombolysis in cerebral infarction grade 2b-3). Patients were divided into high NPR (>35; n=115) and low NPR (≤35; n=81) groups. Results: The FR rate was significantly higher in the high NPR group than low NPR group (81.74vs 55.56%;p=0.000). NPR was independently associated with FR (odds ratio: 2.107; 95% CI: 1.017-4.364; p=0.045). Conclusion: High NPR was associated with the risk of FR in patients with acute ischemic stroke due to large vascular occlusions.