Abstract

PurposeWomen with different BMI, age and comorbidities seek for breast reconstruction. It is critical to understand the risk associated with each technique to ensure the most appropriate method and timing is used. Outcome after reconstructions have been studied, but consensus is lacking regarding predictive risk factors of complications. The authors present their experience of different autologous and alloplastic reconstructions with an emphasis on predictors of complications.MethodsProspectively maintained reconstruction database from 2008 to 2019 was reviewed. Factors associated with complications were identified using logistic regression, multinomial logistic regression and risk factor score to determine predictors of complications.ResultsA total of 850 breast reconstructions were performed in 793 women, including 447 DIEP, 283 LD, 12 TMG and 51 implant reconstructions. Complications included minor (n = 231, 29%), re-surgery requiring (n = 142, 18%) and medical complications (n = 7, 1%). Multivariable analysis showed that complications were associated independently with BMI > 30 (OR 1.59; 95% CI 1.05–2.39, p = 0.027), LD technique (OR 4.05; 95% CI 2.10–7.81, p < 0.001), asthma or chronic obstructive pulmonary disease (OR 2.77; 95% CI 1.50–5.12, p = 0.001) and immediate operation (OR 0.69; 95% CI 0.44–1.07, p = 0.099). Each factor contributed 1 point in the creation of a risk-scoring system. The overall complication rate was increased as the risk score increased (35%, 61%, 76% and 100% for 1, 2, 3 and 4 risk scores, respectively, p < 0.001).ConclusionsThe rate of complication can be predicted by a risk-scoring system. In increasing trend of patients with medical problems undergoing breast reconstruction, tailoring of preventive measures to patients’ risk factors and careful consideration of the best timing of reconstruction is mandatory to prevent complications and costs.

Highlights

  • Breast conservation therapy is an effective option for patients with early stage breast cancer, many women still undergo mastectomy for either cancer treatment or prophylaxis [1]

  • A total of 850 breast reconstructions were performed in 793 women during the study period

  • We found that Body mass index (BMI) > 30, asthma/chronic obstructive pulmonary disease (COPD), latissimus dorsi (LD) technique and immediate reconstruction were significantly associated with postoperative complications

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Summary

Introduction

Breast conservation therapy is an effective option for patients with early stage breast cancer, many women still undergo mastectomy for either cancer treatment or prophylaxis [1]. BMI, age and comorbidities seek for breast reconstruction. Breast Cancer Research and Treatment (2020) 182:345–354 reconstructive options available, it is critical to understand the risk associated with each reconstructive technique to ensure that the most appropriate method is used. Every breast reconstruction method is associated with its own surgical complication profile and its own impact on quality of life [5]. Satisfaction with outcome and quality of life after reconstructions have been widely studied [1, 3,4,5,6,7], but consensus is lacking in the literature regarding differences in complication rates after different reconstructions [2]. Data are available concerning surgical site infection and noninfectious complications after breast reconstruction in different techniques. Certain comorbid conditions and postoperative complications have been assessed but studies are limited regarding predictive risk factors of complications

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