Abstract
ObjectiveThe aim of this study was to develop a predictive model of objective oropharyngeal obstructive sleep apnea (OSA) surgery outcomes including success rate and apnea-hypopnea index (AHI) reduction ratio in adult OSA patients.Study designRetrospective outcome research.MethodsAll subjects with OSA who underwent oropharyngeal and/or nasal surgery and were followed for at least 3 months were enrolled in this study. Demographic, anatomical [tonsil size (TS) and palate-tongue position (PTP) grade (Gr)], and polysomnographic parameters were analyzed. The AHI reduction ratio (%) was defined as [(postoperative AHI—preoperative AHI) x 100 / postoperative AHI], and surgical success was defined as a ≥ 50% reduction in preoperative AHI with a postoperative AHI < 20.ResultsA total of 156 consecutive OSAS adult patients (mean age ± SD = 38.9 ± 9.6, M / F = 149 / 7) were included in this study. The best predictive equation by Forward Selection likelihood ratio (LR) logistic regression analysis was:ln(Px1−Px)=1.518−0.039×Age+1.392×TSGr−0.803×PTPGrThe best predictive equation according to stepwise multiple linear regression analysis was: AHIreductionratio=−39.464+(32.752×TSGr)+(2.623×AHI)−(2.542×Arousalindex)+[1.245×MinimumSaO2(%)]−[0.599×Snoring(%)] (TS/PTP Gr = 1 if TS/PTP Gr 3 or 4, TS/PTP Gr = 0 if TS/PTP Gr 1 or 2)ConclusionThe predictive models for oropharyngeal surgery described in this study may be useful for planning surgical treatments and improving objective outcomes in adult OSA patients.
Highlights
Obstructive sleep apnea (OSA) is characterized by repeated episodes of a significant reduction or complete cessation in breathing during sleep, and is caused by a narrowing or obstruction of the upper airway, including the nasal cavity, pharynx and larynx.[1]
The predictive models for oropharyngeal surgery described in this study may be useful for planning surgical treatments and improving objective outcomes in adult OSA patients
There are a variety of therapeutic options for OSA such as positional therapy, surgery, weight loss, positive airway pressure (PAP), and oral appliance (OA)
Summary
Obstructive sleep apnea (OSA) is characterized by repeated episodes of a significant reduction or complete cessation in breathing during sleep, and is caused by a narrowing or obstruction of the upper airway, including the nasal cavity, pharynx and larynx.[1] If detection or management is neglected, OSA can lead to various symptoms including excessive daytime sleepiness and serious consequences such as cardiovascular disease.[2, 3] prompt diagnosis and optimal treatment for OSA is important for improving patient health. [4] In general, the optimal treatment method is determined according to the patient’s anatomical structures (e.g., tongue, tonsil, soft palate, adenoid, nasal septum, inferior turbinate), polysomnographic results (e.g., apnea-hypopnea index [AHI], arterial oxygen saturation [SaO2]) and personal preferences.[5] There are a variety of therapeutic options for OSA such as positional therapy, surgery, weight loss, positive airway pressure (PAP), and oral appliance (OA). [4] In general, the optimal treatment method is determined according to the patient’s anatomical structures (e.g., tongue, tonsil, soft palate, adenoid, nasal septum, inferior turbinate), polysomnographic results (e.g., apnea-hypopnea index [AHI], arterial oxygen saturation [SaO2]) and personal preferences.[5]
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
