Abstract
Rationale: Various factors affect attrition in trials including non-compliance to the protocol, premature discontinuation of intervention, and early dropout. To ensure adequate power, prior to terminating enrollment, an evaluation of the likely attrition rate at the end of the trial is made. In most cases, such assessment occurs early in the study when few subjects have completed. Therefore, the objective of this project is to obtain an accurate estimate of the evaluable rate based on limited observed data.
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