Abstract

Diabetes is a chronic non-communicable disease resulting from pancreatic inability to produce the hormone insulin, or a physiological cellular inability to use this hormone effectively. This leads to unregulated blood glucose levels, which can cause significant and often irreversible physiological damage. Current means of glucose level monitoring range from infrequent capillary blood glucose sampling to continuous interstitial fluid glucose monitoring. However, the accuracy of these methods is limited by numerous factors. A potential solution to this shortcoming involves the use of wearable sensors that record an individual’s physiological responses to a range of daily activities, which are subsequently fused and processed with machine learning (ML) algorithms to provide a prediction of an individual’s glucose level and can provide an artificial intelligence-driven glucose monitoring platform. In this paper, we conduct a comparison case study using quadratic discriminant analysis (QDA) and support vector machine (SVM) algorithms for the classification of glucose levels with data acquired from the wearable sensors of a type 1 diabetic individual. Preliminary results demonstrate predicted glucose levels with >70% accuracy, indicating potential for this approach to be used in the design of an ergonomic glucose prediction platform utilizing wearable sensors. Further work will involve the exploration of additional datasets from affordable wearables to enhance and improve the prediction power of the ML algorithms.

Highlights

  • Type 1 diabetes (T1D) is a chronic condition which can develop at any stage of life

  • This paper aims to contribute to the pool of machine learning (ML) literature for diabetes monitoring by using lifestyle data from an ergonomic wearable device to observe the extent to which glucose levels can be predicted with the application of the discriminant analysis and a support vector machine (SVM) algorithm for type 1 diabetes

  • The device possesses a data storage capacity of up to 4 GB and a charge time of 1–2 h which provides 5 days’ worth of battery life, and it is able to provide a number of lifestyle parameters to its users which range from direct measures to inferred estimation, spanning sleep tracking, number of steps climbed, heart rate monitor, calories burned, stress levels, distance covered, rate of oxygen expended during exercise and blood oxygen

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Summary

Introduction

Type 1 diabetes (T1D) is a chronic condition which can develop at any stage of life. It is defined as an autoimmune condition caused by the destruction of pancreatic β-cells and requires the administration of manufactured biosimilar insulin for survival [1,2]. Insulin is responsible for maintaining biological homeostasis by enabling glucose to enter cells as their primary energy source. In the UK, 4.1 million people live with diabetes, while a further 850,000 are currently undiagnosed. Global estimates identify 1 in 11 people as having diabetes. Unregulated glucose levels cause significant, and often irreversible, damage to blood vessels in the eyes, kidneys, teeth, and skin

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