PREDICTIVE FACTORS OF MASKED HYPERTENSION IN TYPE 2 DIABETES

Abstract

Objective: - Primary objective: to identify masked hypertension predictive risk factors in normotensive type 2 diabetic patients in clinical measurement. Design and method: This was a case-control study. We performed 24-hour ambulatory BP in 358 type 2 diabetic patients normotensive in clinical measurement. We compared both Masked Hypertension and Normotensive groups according to clinical/laboratory parameters and target organ damage, and identify MH predictor risk factors among diabetic population Results: The percentage of participants with masked hypertension was 30,7%, in 54,5% of the cases, it is a noctural hypertension. 38,2% of the masked hypertension patients has normal high blood pressure in routine office measurement, 53,63 % of our MH are obese, 64,5% had metabolic syndrome as classified by NCEP/ATP III. Predictors of masked hypertension are: Normal high blood pressure in consultation, the presence of left ventricular hypertrophy and a microalbuminuria. In this hypertensive masked population, target organs achievement is frequent: 6,8% have peripheral arterial disease, 64,8% have left ventricular hypertrophy, 48% have microalbuminuria, 72,9% have intima-media thickness > 0,9 and 56,3% have arterial stiffness evidence by a PWV> 10 m/sec. Conclusions: Predictive factors assessment for masked hypertension helps to better assess cardiovascular risk in normotensive type 2 diabetic patients in routine practice.