Predictive Factors for Improved Renal Function in Renal Transplantation Recipients

Abstract

ObjectiveThe purpose of this study is to analyze varying predictive factors for improved graft function among renal transplant recipients. MethodsTwo hundred eleven consecutive donor and recipient pairs who underwent renal transplantation between January 2011 and December 2015 were enrolled in our study. Factors that affected renal graft function were analyzed. Statistical analyses were performed using SPSS version 16.0 software (SPSS Inc, Chicago, IL, United States). ResultsThe mean age of donors in years was 30 (range, 17-62), with a mean body mass index (BMI) of 23.20 kg/m2 (range, 16.10-39.50). Mean total warm ischemic time in minutes was 44.80 (range, 26.10-83.45). The mean age of the recipients in years was 48 (range, 12-78) with a mean BMI of 22 kg/m2 (range, 14.80-37.30). Estimated glomerular filtration rate at 6 and 12 months post-transplantation were 69 mL per minute per 1.73 m2 (range, 10-137) and 65 (range, 16-110), respectively. Based on several parameters, there was no significant factor that improved renal graft function at 6 and 12 months after transplant. Total warm ischemic time almost showed statistical significance in predicting improved renal graft function after transplant. Future study with a longer period of observation and a larger sample size should be done for further investigation. ConclusionsTotal warm ischemic time is a promising parameter to predict improved renal graft function post-transplantation.