Abstract
Brachytherapy has been used for the treatment of prostate cancer for nearly 100 years. Low dose rate brachytherapy, the permanent placement of radioactive seeds (e.g., Iodine-125 or Pallidium-103) within the prostate, is an effective treatment for men with clinically localized low-risk prostate cancer. Brachytherapy can also be delivered by temporarily inserting high energy radioactive isotopes (e.g., Iridium-192) into the prostate. This technique is referred to as high dose-rate brachytherapy. The ability of brachytherapy to directly deliver radiation within the prostate while limiting the dose delivered to surrounding normal tissues is a significant advantage of this treatment (1).
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