Abstract
Objective: To examine the value of the cervical length (CL) measurement at 24-30 gestational weeks in the prediction of spontaneous preterm delivery (SPD) between 30 and 34 weeks (SPD<sub>34</sub>) and between 34 and 37 weeks (SPD<sub>37</sub>). Methods: We performed a prospective cross-sectional study. CL was measured once by transvaginal ultrasound examination between 24 and 30 weeks. Results: The study sample consisted of 1,180 low-risk singleton pregnancies. 10 women (0.85%) had a SPD<sub>34</sub> and 60 (5.08%) had a SPD<sub>37</sub>. CL was shorter (p < 0.001) in the women who had a SPD<sub>34</sub> (median 11 mm) compared to the women who delivered after 34 weeks (median 31 mm). CL was shorter (p < 0.001) in the women who had a SPD<sub>37</sub> (median 22 mm) compared to the women who delivered after 37 weeks (median 31 mm). CL predicted SPD<sub>34</sub> (OR = 0.837, R<sup>2</sup> = 0.2768, AUC = 0.9406, p < 0.001) and SPD<sub>37</sub> (OR = 0.907, R<sup>2</sup> = 0.1085, AUC = 0.7584, p < 0.001). The model achieved a sensitivity of 70.0 and 38.3% for 10% false-positive rate for SPD<sub>34</sub> and SPD<sub>37</sub>, respectively. Conclusions: CL after 24 weeks is significantly shorter in women destined to have a SPD. In low-risk singleton pregnancies CL performs very well in predicting SPD<sub>34</sub> and adequately in predicting SPD<sub>37</sub>.
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