Prediction of Mortality and Major Cardiac Events by Exercise Echocardiography in Patients with Normal Exercise Electrocardiographic Testing: Bouzas-Mosquera A, Peterio J, Alvarez-Garcia N, et al. J Am Coll Cardiol 2009;53:1981–90

Abstract

Given that exercise-induced wall motion abnormalities appear earlier in myocardial ischemia than ST-segment changes, this study evaluated the use of exercise echocardiography (EE) to predict outcomes in patients with known or suspected coronary artery disease (CAD) and normal exercise electrocardiogram (ECG) testing. The study examined 4004 patients with known or suspected CAD and ECG changes at rest who had no evidence of myocardial ischemia during exercise ECG testing. The investigators divided these 4004 patients into two groups: history of CAD and no history of CAD.