Prediction of disease causing gene in Xq22.1 region of human X-chromosome

Abstract

A comprehensive analysis of the X-chromosome led to the discovery of an important region found to be Xq22.1. Xq22.1 was analysed in detail to locate a credible gene carrying segment on it, which may be implicated in various disorders related to the X-chromosome. Finding genes in a genomic sequence is a fiddly problem. Hence, we developed a new in-silico approach to identify the novel gene, based on homology methods (extrinsic methods) and gene prediction methods (intrinsic methods).