Prediction of Cis Regulatory Elements in the Genome of Synechococcus Elongatus PCC 6301

Abstract

Identification of putative cis regulatory elements by comparative analysis of genomes helps us to understand mechanism of global gene expression. Many approaches were previously used for identification of cis regulatory elements. Here we use phylogenetic foot-printing analysis and MEME suite for predicting cis regulatory elements in the genome of Synechococcus elongatus sp. PCC6301. We have identified total 102 putative cis regulatory elements, in which several of them were previously described, experimentally, while several motifs were new. As many motifs which were identified in the current computational predictions were previously reported, it is highly likely that the new ones would act as cis regulatory elements. The newly identified ones are target for experimental validation and to build gene regulatory network in the genome of Synechococcus elongatus. Keywords Cis regulatory elementsPhylogenetic foot printing: MEMEMASTGene expression