Prediction of acute-on-chronic liver failure and integrated traditional Chinese and Western medicine therapy

Abstract

Acute-on-chronic liver failure(ACLF) is a reversible and complex clinical syndrome caused by various factors in patients with pre-existing chronic liver diseases,with the clinical features of acute liver function decompensation and high short-term mortality rate.ACLF has a complex pathogenesis,rapid progression,and a dangerous prognosis,and early and accurate prediction of prognosis is of vital importance. At present,there is still no ideal therapy for ACLF,and in recent years,integrated traditional Chinese and Western medicine therapy has achieved a certain effect in the treatment of this disease. This article reviews the advances in prognostic evaluation and integrated traditional Chinese and Western medicine therapy for ACLF,in order to provide guidance to prognostic evaluation of ACLF and selection of the regimens of integrated traditional Chinese and Western medicine therapy.