Prediction model and risk factors of OSAHS in snoring patients

Abstract

Objective This study was designed to analyze risk factors in patients with snoring and obstructive sleep apnea hypopnea syndrome (OSAHS), to establish OSAHS prediction model, and to find indicators that can be used to determine the severity of the disease simply. Methods There were 592 patients who underwent polysomnography in the Sleep Monitoring Room of Zigong Fourth People′s Hospital were selected as subjects.Among them, there were 178 cases in snoring group and 414 cases in OSAHS group.Age, sex, height, weight, body mass index (BMI), neck circumference, waist circumference, snoring degree and Epworth score were recorded by questionnaire and scale.The difference of clinical data between snoring patients and OSAHS patients was analyzed, and found out the risk factors for OSAHS.The correlation analysis was used to analyze the correlation between the risk factors and the apnea hypopnea index (AHI) and lowest pulse oxygen saturation (SpO2). The prediction model of the severity of OSAHS was established by means of multiple stepwise regression analysis. Results The results showed that gender, age, BMI, neck circumference, waist circumference, snoring degree and Epworth score were risk factors for OSAHS.Correlation analysis showed that these risk factors were significantly correlated with the AHI and lowest SpO2.The prediction model obtained by multiple stepwise regression analysis were: AHI=2.338×BMI+ 9.378×snoring degree+ 1.42×Epworth score+ 1.235×neck circumference -103.415; lowest SpO2=- 1.309×BMI -0.631×Epworth score -3.63×snoring degree+ 3.432×sex+ 118.504 (male for 1, female for 2). Conclusions BMI, neck circumference, sex, snoring degree and Epworth score are independent risk factors of OSAHS.The risk factors of OSAHS can be introduced into the prediction model to estimate the severity of the disease, which is helpful for early diagnosis and treatment. Key words: Snoring; Risk factors; Sleep apnea, obstructive; Prediction model