Abstract
Natural Killer (NK) cells are the most abundant immune cells at the time of implantation and early stage of pregnancy in uterine endometrium and decidua. NK cells have important roles in the achievement and maintenance of pregnancy. NKp46, an NK cell receptor, is involved in cytotoxicity and cytokine production. We have previously reported the lower expression of NKp46 on uterine and peripheral blood NK cells in women with reproductive failures, such as repeated implantation failures or recurrent pregnancy loss (RPL).
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