Abstract

Objectives: The purpose of this study was to determine the effectiveness of Test of Infant Motor Performance (TIMP) in detecting motor developmental delay in preterm infants. Material and methods: The present study was conducted on 30 infants born preterm with corrected age of 2 months and follow up of TIMP at 4 months corrected age and Alberta Infant Motor Scale (AIMS) at 2, 4 and 6 months corrected age. Study period was January 2012 to December 2015. Results: Pearson product moment correlation coefficient used to assess the relationship between the raw scores of TIMP and AIMS percentilerank at corrected age of 2 and 4 months, was 0.757 (p<0.0001) and 0.874 (p<0.0001) respectively. An analysis of the sensitivity, specificity, positive predictive value and negative predictive value of various TIMP cutoff scores for comparison with AIMS scores above and below the 10th percentile revealed the best TIMP score with a cutoff of -1 standard deviation below the mean. The results for comparison of 2, 4, 6 months corrected age AIMS data using Pearson chi square test was highly significant with p 0.001 at 2months CA AIMS data with 4 months CA AIMS data. Conclusion and Interpretation: TIMP and AIMS are equally useful in the assessment of infant motor performance at 4 months of corrected age. A cutoff score of -1 SD from the mean on TIMP was a better predictor of developmental outcome in this study.

Highlights

  • The word “preterm” is used to refer to infants born before 37 completed weeks of gestation [1].Preterm is defined as less than 37 weeks, very preterm is less than 32 weeks, and extremely preterm is defined as less than 28 weeks gestation[2]

  • Advances in antenatal medicine and neonatal intensive care, including more aggressive delivery room resuscitation, Manuscript received: 09th September 2017 Reviewed: 16th September 2017 Author Corrected: 23rd September 2017 Accepted for Publication: 30th September 2017 surfactant use, antenatal corticosteroid utilization, improved ventilator techniques, and nutritional management have successfully resulted in improved survival rates of preterm infants

  • The results of this study were analyzed in terms of Sensitivity, Specificity, Positive Predictive Value (PPV), Negative Predictive Value (NPV) and diagnostic accuracy which were measured using Test of Infant Motor Performance (TIMP) and Alberta Infant Motor Scale (AIMS)

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Summary

Introduction

The word “preterm” is used to refer to infants born before 37 completed weeks of gestation [1].Preterm is defined as less than 37 weeks, very preterm is less than 32 weeks, and extremely preterm is defined as less than 28 weeks gestation[2]. Survival remains directly proportional to gestational age and birth weight. Advances in antenatal medicine and neonatal intensive care, including more aggressive delivery room resuscitation, Manuscript received: 09th September 2017 Reviewed: 16th September 2017 Author Corrected: 23rd September 2017 Accepted for Publication: 30th September 2017 surfactant use, antenatal corticosteroid utilization, improved ventilator techniques, and nutritional management have successfully resulted in improved survival rates of preterm infants. Improvements in survival have not been accompanied by proportional reductions in the incidence of disability in this population. Survival is not an adequate measure of success in these infants who remain at high risk for neurodevelopmental and behavioral morbidities

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