Predicting stroke events with a proactive fusion system: a comprehensive study on imbalance class handling in computational biomechanics

Abstract

Stroke, as a critical global health concern and the second leading cause of death, occurs when blood flow to the brain is interrupted. Although machine learning has advanced in medical safety, there is limited research on stroke prediction using information fusion systems. This study presents a fusion framework that combines multiple base classifiers and a Meta classifier to improve stroke prediction performance. The research utilizes Grid Search optimized models, such as Random Forest, Support Vector Machine, K Nearest Neighbors, AdaBoost, Gradient Boosting, Light Gradient Boosting, Categorical Boosting, and eXtreme Gradient Boosting for in-depth stroke analysis. Since stroke events are rare and unpredictable, classification outcomes can be deceptive due to imbalanced data. This article examines stroke probability by comparing three data balancing methods: over-sampling, under-sampling, and tomek-link synthetic minority over-sampling (SMOTE-TL) to enhance prediction accuracy. The findings reveal that AdaBoost as a meta-classifier attains the highest performance in the fusion framework, with a peak of 88.09% Recall and 83.66% F1 score. This innovative approach provides crucial insights into stroke prediction and can be a valuable resource for strengthening intervention efforts in advanced healthcare systems.