Abstract

Background: Chronic Obstructive Pulmonary Disease (COPD) becomes burdensome and reduces the quality of life in COPD patients and their families. Understanding the factors affecting the quality of life could improve the process of care and treatment of these patients. Therefore, this study aimed to investigate the factors that influence and can predict the quality of life in COPD patients. Methods: A total of 281 COPD patients were included and analyzed by spirometry measurement, BODE index and its components (body mass index; BMI, forced expiratory volume in one second % predicted; FEV1%predicted, dyspnea score of the modified Medical Research Council; mMRC, and distance in the six-minute walking test; 6MWT).Quality of life was assessed by the St. George’s Respiratory Questionnaire (SGRQ). Results: The total SGRQ score was 42.1±17.4. The mMRC dyspnea score, ABCD group classification of COPD and BODE index moderately correlated with the total SGRQ score. Weak correlations were found between BMI, FEV1%predicted and 6MWT. Multiple regression analysis showed that the mMRC dyspnea score, BODE index, age, and COPD group D were important predictors of quality of life in COPD patients with R2 of 0.467. Conclusion: The mMRC dyspnea score, BODE index, age, and COPD group D could predict the quality of life in the COPD patients in this study.

Highlights

  • Chronic Obstructive Pulmonary Disease (COPD) is one of the most important diseases, which affects more than 200 million people worldwide [1]

  • A total of 281 COPD patients were included for analyses

  • Equation multiple regression models could predict quality of life at 46.7%, and it was found that the modified Medical Research Council (mMRC) dyspnea score, BODE index, age and COPD group D could predict quality of life in COPD patients

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Summary

Introduction

Chronic Obstructive Pulmonary Disease (COPD) is one of the most important diseases, which affects more than 200 million people worldwide [1]. COPD is a preventable and treatable disease characterized by persistent respiratory symptoms and airflow limitation [4]. These characteristics lead to deconditioning, Quality of life is important in measuring the impact of chronic diseases [11]. Chronic Obstructive Pulmonary Disease (COPD) becomes burdensome and reduces the quality of life in COPD patients and their families. Understanding the factors affecting the quality of life could improve the process of care and treatment of these patients. This study aimed to investigate the factors that influence and can predict the quality of life in COPD patients

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