Predicting miRNA-lncRNA interactions on plant datasets based on bipartite network embedding method.

Abstract

The research of miRNA-lncRNA interactions (MLIs) has received great attention recently due to their vital roles in microbiology and profound significance in diseases. Currently, many related studies mainly focus on animals and the link prediction problem on plants is rarely discussed comprehensively. Motivated by this, we achieve link prediction task based on the concept of bipartite graph and verify encouraging performance of our conclusions by conducting experiments on plant datasets. In this work, we firstly extract attribute information and structure information as base features and further process these information for network embedding. Intra-partition and inter-partition proximity modelling are conducted to construct the loss function, which facilitates the training of parameters. Finally, the superiority of our presented approach is shown by carrying out experiments on four plant datasets, which reflects the significance of this work to the research of microbiology and disease.