Predicting Hospitalization By Tapse/Spap and the Role of Spironolactone in Asymptomatic Heart Failure Patients

Abstract

Aim: To appraise the prediction of tricuspid annular plane systolic excursion (TAPSE)/systolic pulmonary artery pressure (SPAP)with regard to hospitalization and the effect of spironolactone use. Materials & methods: Atotal of 245 patients were evaluated for the study. Patients were followed for 1 year and cardiovascular outcomes were determined. Results: It was determined that TAPSE/SPAP was an independent predictor of hospitalization. A 0.1-mmHg decrease in TAPSE/SPAP was associated with a 9% increase in relative risk. No event was observed above the 0.47 level. Negative correlation with TAPSE (uncoupling) began in the spironolactone group when SPAP was ≥43 and innonusers when SPAP was 38 (Pearson's correlation coefficient: -,731 vs -,383; p<0.001 vs p=0.037). Conclusion: TAPSE/SPAP measurement may be useful in predicting 1-year hospitalization in asymptomatic heart failure patients. This ratio was also found to be higher in patients who used spironolactone.