Abstract

In recent years, endogenous and xenobiotic metabolism has been one of the cutting edge topics of our journal (Hengstler and Bolt 2008; Bolt and Hengstler 2007, 2008a, b). Because of the dynamic progress in the field of drug metabolizing enzymes, we have initiated a new series of review articles that focus on nomenclature, substrate specificities, genetic organization, polymorphisms, clinical relevance and role in carcinogenesis (Pelkonen et al. 2008; Lankisch et al. 2008; Strassburg et al. 2008; Decker et al. 2009; Adam and Laufs 2008; Macdonald and Gledhill 2007). In order to give our readers a better overview over the numerous articles published in the field of drug metabolism in our journal during the past 2 years, we summarize their key messages and link them to the respective articles (Table 1).

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