Abstract

BackgroundThe COVID-19 pandemic has highlighted the inability of health systems to leverage existing system infrastructure in order to rapidly develop and apply broad analytical tools that could inform state- and national-level policymaking, as well as patient care delivery in hospital settings. The COVID-19 pandemic has also led to highlighted systemic disparities in health outcomes and access to care based on race or ethnicity, gender, income-level, and urban-rural divide. Although the United States seems to be recovering from the COVID-19 pandemic owing to widespread vaccination efforts and increased public awareness, there is an urgent need to address the aforementioned challenges.ObjectiveThis study aims to inform the feasibility of leveraging broad, statewide datasets for population health–driven decision-making by developing robust analytical models that predict COVID-19–related health care resource utilization across patients served by Indiana’s statewide Health Information Exchange.MethodsWe leveraged comprehensive datasets obtained from the Indiana Network for Patient Care to train decision forest-based models that can predict patient-level need of health care resource utilization. To assess these models for potential biases, we tested model performance against subpopulations stratified by age, race or ethnicity, gender, and residence (urban vs rural).ResultsFor model development, we identified a cohort of 96,026 patients from across 957 zip codes in Indiana, United States. We trained the decision models that predicted health care resource utilization by using approximately 100 of the most impactful features from a total of 1172 features created. Each model and stratified subpopulation under test reported precision scores >70%, accuracy and area under the receiver operating curve scores >80%, and sensitivity scores approximately >90%. We noted statistically significant variations in model performance across stratified subpopulations identified by age, race or ethnicity, gender, and residence (urban vs rural).ConclusionsThis study presents the possibility of developing decision models capable of predicting patient-level health care resource utilization across a broad, statewide region with considerable predictive performance. However, our models present statistically significant variations in performance across stratified subpopulations of interest. Further efforts are necessary to identify root causes of these biases and to rectify them.

Highlights

  • BackgroundThe COVID-19 pandemic has impacted the health and well-being of individuals, communities, and economies worldwide at an unprecedented scale [1,2]

  • This study presents the possibility of developing decision models capable of predicting patient-level health care resource utilization across a broad, statewide region with considerable predictive performance

  • In the United States, the COVID-19 pandemic has highlighted (1) the inability of health systems to leverage existing system infrastructure in order to rapidly develop and apply broad analytical tools that could inform state- and national-level policymaking and patient care delivery in hospital settings and (2) systemic disparities in COVID-19–related outcomes and access to care based on race or ethnicity [4], gender [5], income level, and urban-rural divide [6,7]

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Summary

Introduction

BackgroundThe COVID-19 pandemic has impacted the health and well-being of individuals, communities, and economies worldwide at an unprecedented scale [1,2]. At the peak of the pandemic outbreak in the United States, these limitations contributed to distrust, misinformation, and lack of cohesive decision-making This impeded local government and public health officials from making informed policy decisions, such as mask-wearing mandates and stay-at-home orders, to control disease outbreaks and safeguard health systems from extended strain. This led to shortages in hospital beds, personal protective equipment, and health care personnel, thereby causing significant disruptions to health care delivery and consequent loss of lives [2,3].

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