Predicting coronary graft occlusion in males with type 2 diabetes: an annual prospective study

N S Lisytenko,N A Morova,V N Tsekhanovich

doi:10.25207/1608-6228-2020-27-4-189-200

N S Lisytenko, N A Morova + Show 1 more

Open Access

https://doi.org/10.25207/1608-6228-2020-27-4-189-200

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Abstract

Aim. Identiﬁcation of factors affecting coronary bypass graft patency in patients with type 2 diabetes (T2D) during one year after coronary bypass grafting.Materials and methods. Coronary artery bypass grafting for stable effort angina was ordered in 23 men with T2D. The patients had transthoracic echocardiogram before surgery. All patients were veriﬁed for lupus anticoagulant (LA) in blood on the 14th day after surgery. A year later, the patients underwent coronary shuntography to assess bypass patency.Results. LA was detected in 15 of 23 patients (65%). One year after surgery, occlusions of coronary shunts were revealed in 10 of 23 patients. In patients with coronary shunt occlusions, end-diastolic and end-systolic dimensions, end-diastolic and end-systolic volumes, end-systolic and end-diastolic indices (EDD, ESD, EDV, ESV, ESI, EDI, respectively), as well as the LA ratio signiﬁcantly exceeded those in patients without occlusions (Mann—Whitney p values 0.004, 0.012, 0.012, 0.006, 0.006, 0.004, 0.017, respectively). A method is proposed for predicting coronary shunt occlusions based on assessment of end-diastolic volume of left ventricle and the LA ratio.Conclusion. Echocardiographic values for left ventricle (EDD, ESD, EDV, ESV, ESI, EDI) and the LA ratio are predictors of coronary graft occlusions in patients with type 2 diabetes.

Highlights

In patients with coronary shunt occlusions, end-diastolic and end-systolic dimensions, end-diastolic and end-systolic volumes, end-systolic and end-diastolic indices (EDD, ESD, EDV, ESV, ESI, EDI, respectively), as well as the lupus anticoagulant (LA) ratio significantly exceeded those in patients without occlusions (Mann—Whitney p values 0.004, 0.012, 0.012, 0.006, 0.006, 0.004, 0.017, respectively)
A method is proposed for predicting coronary shunt occlusions based on assessment of end-diastolic volume of left ventricle and the LA ratio
Ji Q., Xia L.M., Shi Y.Q., Ma R.H., Shen J.Q., Ding W.J., Wang C.S. Impact of severe left ventricular dysfunction on in-hospital and mid-term outcomes of Chinese patients undergoing first isolated off-pump coronary artery bypass grafting

Summary

Introduction

Echocardiographic values for left ventricle (EDD, ESD, EDV, ESV, ESI, EDI) and the LA ratio are predictors of coronary graft occlusions in patients with type 2 diabetes. У пациентов с сахарным диабетом 2-го типа (СД2) окклюзии коронарных шунтов в первый месяц и в первый год после операции наблюдаются значимо чаще в сравнении с лицами без диабета [3, 5]. Среди обследованных пациентов не было выявлено статистической связи между фактом окклюзии шунта и рецидивом стенокардии в первый год после КШ — р для критерия Фишера 0,417.

Results

Conclusion