Abstract
Background: Peripheral precocious puberty (PPP) is defined as the early pubertal maturation independent of gonadotropin stimulation. Autonomous ovarian cysts can be a cause of PPP or isolated precocious menarche. The differential diagnosis of ovarian cysts is important because of distinct management options. Case: A 9 7/12-year-old girl presented because of rapid evolution of breast development and premature menarche. Estrogen levels were elevated while GnRH stimulation test revealed a blunt response. Pelvic sonogram demonstrated an ovarian cyst. She was started on oral letrozole. There was no further episode of menstruation. The cyst resolved spontaneously after three months. Summary and Conclusion: Functional ovarian cysts usually regress spontaneously. This case highlights the effectiveness of letrozole therapy in promptly decreasing estrogen levels and immediately controlling menstrual bleeding
Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
