Abstract
Precision Medicine: What Do We Expect in the Scope of Basic Biomedical Sciences?
Highlights
Deeper about other useful data and well-thought tasks in addition to genome sequences, as well as new synthesis as to how to acquire novel data and to interpret them with wisdom [5,6,7]
Transcriptomics is well-respected as a critical paradigm for gene expression study tailored to cells [15], not yet has a single standard human transcriptome been produced, claimed, validated, and hosted in an authorized database
The Human Transcriptomes Project will certainly come after the sequencing effort in the early phase of the Precision Medicine (PM) project, or being a sequel of it or maybe even sooner, as the current sequencing capacity and tasks will have to be redirected after the genome sequencing effort reaches a peak
Summary
Deeper about other useful data and well-thought tasks in addition to genome sequences, as well as new synthesis as to how to acquire novel data and to interpret them with wisdom [5,6,7]. Once we have an enormous amount of highquality sequences, understanding the human population structures and defining haplotypes within and between populations, as well as their disease relevance, are of essence. Mutation biases can be further used to define function-selected sequence elements beyond proteincoding sequences [9,10].
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