Abstract

In his 2015 State of the Union address, American President Barack Obama announced the Precision Medicine Initiative as a “bold new research effort to revolutionize how we improve health and treat disease.” This was perhaps the first time the general population was exposed to the greater concept of precision medicine and capped years of escalating hype amongst the scientific community. Nearly 2 years later, as the luster of precision medicine has faded, the scientific research community has recoiled from overly optimistic expectations. Thus began the onerous introspective search for systematic flaws that have limited the realization of the full potential of all that precision medicine promises to offer. In a recent policy forum piece published in Science , Hey and Kesselheim argue that the current system is invalid and the process by which scientific discoveries are …

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