Precision and dissipation of a stochastic Turing pattern.

Abstract

Spontaneous pattern formation is a fundamental scientific problem that has received much attention since the seminal theoretical work of Turing on reaction-diffusion systems. In molecular biophysics, this phenomenon often takes place under the influence of large fluctuations. It is then natural to inquire about the precision of such pattern. In particular, spontaneous pattern formation is a nonequilibrium phenomenon, and the relation between the precision of a pattern and the thermodynamic cost associated with it remains largely unexplored. Here, we analyze this relation with a paradigmatic stochastic reaction-diffusion model, i.e., the Brusselator in one spatial dimension. We find that the precision of the pattern is maximized for an intermediate thermodynamic cost, i.e., increasing the thermodynamic cost beyond this value makes the pattern less precise. Even though fluctuations get less pronounced with an increase in thermodynamic cost, we argue that larger fluctuations can also have a positive effect on the precision of the pattern.