Abstract
Early stage cancer of the bile duct system is still difficult to diagnose. In cases of suspect lesions astepwise diagnostic procedure consisting of computed tomography (CT), magnetic resonance imaging (MRI) with MR cholangiography (MRC) and possibly endoscopic retrograde cholangiopancreatography (ERCP) with brush cytology should immediately be carried out. If there is asufficient suspicion for premalignancy or early stage cancer the indications for surgical intervention should clearly be defined. Only resection can lead to adecrease in the recurrence rate and abetter long-term outcome. If the patient is in afunctionally nonresectable condition the possibility of liver transplantation should be considered.
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