Abstract

INTRODUCTION: Tuberculosis (TB) is still a serious public health problem in Los Angeles County, California. Approximately one-third of California's multi-drug-resistant (MDR) tuberculosis (TB) cases reside in Los Angeles County. MDR-TB is defined as TB resistant to at least both isoniazid (INH) and rifampin (RIF). The treatment of MDR-TB usually requires more toxic, less effective medications for a longer duration. Preventing transmission of MDR-TB is also critical. There has been less emphasis on universal access to laboratory techniques for the rapid diagnosis of TB and rapid drug susceptibility testing, which makes the management of MDR-TB a challenge.

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