Abstract

BackgroundMalaria is one of the most prevalent parasitic diseases in the world and represents a threat to travellers visiting endemic areas. Chemoprophylaxis is the prevention measure used in travel medicine, avoiding clinical manifestations and protecting against the development of severe disease and death.MethodsRetrospective and descriptive analysis of malaria prevention data in travellers was recorded from a travel medicine clinic in São Paulo, Brazil, between January 2006 and December 2010. All the medical records of travellers, who had travelled to areas with risk of disease transmission, including Brazil, were analysed. Demographic characteristics of travellers, travel details and recommendations for preventing malaria were also seen.ResultsDuring the study period, 2836 pre-travel consultations were carried out on 2744 individuals (92 were consulted twice). The most common reasons for travelling were tourism and work. The most common destinations were Africa (24.5%), Europe (21.2%), Asia (16.6%) and locations within Brazil (14.9%). In general prophylaxis against malaria was recommended in 10.3% of all the consultations. African destinations vs Asian, Brazilian and other destinations and length of stay ≤30 days were independently associated with the higher odds of chemoprophylaxis recommendation after the logistic regression.ConclusionThe prophylaxis against malaria was recommended in 10.3% of the consultations. The authors believe that a coherent measure of malaria prevention in Brazil and for international travellers would be to recommend for all parts of the North Brazil, avoidance of mosquito bites and immediate consultation of a physician in case of fever during or after the journey is recommended.

Highlights

  • Malaria is one of the most prevalent parasitic diseases in the world and represents a threat to travellers visiting endemic areas

  • Brazil and Colombia are on track to achieve a 75% decrease in case incidence by 2015, which would predominantly concern Plasmodium vivax malaria transmission [1]

  • The results presented in this study do not represent the overall Brazilian travelling population

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Summary

Introduction

Malaria is one of the most prevalent parasitic diseases in the world and represents a threat to travellers visiting endemic areas. During 2015, there were an estimated 214 million cases of malaria and an estimated 438,000 deaths (range 236,000–635,000) globally [1]. The number of confirmed malaria cases in the region decreased from 1.2 million in 2000 to 427,000 cases in 2013. Reductions of >75% in the incidence of microscopically-confirmed malaria cases were reported in 13 out of 21 countries. Brazil and Colombia are on track to achieve a 75% decrease in case incidence by 2015, which would predominantly concern Plasmodium vivax malaria transmission [1]. Brazilian Amazon concentrates 99.8% of malaria cases in the country, a scenario in which the P. vivax (84%) is the prevalent species. The states of Acre, Amazonas, Pará, Amapá, Roraima and Rondônia

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