Abstract
Hypothesis: We hypothesized pretransplant atherosclerosis predisposes patients to increased risk of acute rejection post-transplant via in heightened occult systemic inflammation. Methods: This was a continuous prospective cohort study, in which pretransplant sera and inferior epi-gastric arterial samples were collected from 63 renal transplant recipients. Serum levels of CRP, neopterin, and CD40 ligand were measured (ELISA). Twenty arterial samples, were selected for histological analysis by an experienced pathologist, completely blinded to all sample identity.
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