Abstract
<h3>Study Objective</h3> Determining safety, feasibility, and validity of transcervical Tru-cut biopsy (TCB) as complementary method in the management of uterine mass with abnormal ultrasound (US) features. <h3>Design</h3> Prospective pilot study. <h3>Setting</h3> Out-patient procedure without the need for anesthesia performed in lithotomic position with 18-gauge disposable core tissue biopsy needle under transvaginal US guidance. <h3>Patients or Participants</h3> Ten premenopausal women with atypical myometrial mass on transvaginal US examination indicated for laparoscopic myomectomy (LM) were included. The myometrial lesion was described using MUSA (Morphological Uterus Sonographic Assessment) criteria. <h3>Interventions</h3> All patients underwent transcervical TCB. Transcervical approach without disruption of the perimetrium was chosen to ensure the oncological safety and exclude dissemination of potentially malignant cells. Three tissue samples of the tumor were collected for histopathological analysis from each patient 2 to 4 weeks prior to the surgery. In case of benign TCB histology result, LM with the use of enclosed morcellation was performed as planned. Acquired specimen was analyzed and both histological results were compared. <h3>Measurements and Main Results</h3> In all 10 cases TCB was feasible and without any peri- or post-procedural complications. The histology results from TCB and LM were identical and non-malignant in all cases. Following histological findings were recorded: conventional leiomyoma in 7 cases, cellular leiomyoma in 1 case, epithelioid leiomyoma in 1 case, leiomyoma with bizarre nuclei in 1 case. <h3>Conclusion</h3> Although small, our pilot data suggest that TCB using the transcervical approach is feasible and safe for patients with planned myomectomy and abnormal US appearance of the uterine mass. TCB can thus provide reliable and precise histopathological data and may allow the surgeon to set up an adequate, mini-invasive, and still maximally safe treatment plan.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
