Abstract
Lucid dreaming is a remarkable state of consciousness in which one is aware of the fact that one is dreaming while continuing to dream. Based on the strong relationship between physiological activation during rapid eye-movement sleep and lucid dreaming, our pilot research investigated whether enhancing cortical activation via acetylcholinesterease inhibition (AChEI) would increase the frequency of lucid dreams and found AChEI to be a promising method for lucid dream induction. In the current study we sought to quantify the size and reliability of the effect of AChEI on lucid dreaming, dream recall and dream content as well as to test the effectiveness of an integrated lucid dream induction protocol which combined cholinergic stimulation with other methods for lucid dream induction. Participants (N = 121) with high dream recall and an interest in lucid dreaming were randomly assigned counterbalanced orders of 3 doses of galantamine (0, 4 and 8 mg). On 3 consecutive nights, they awoke approximately 4.5 hours after lights out, recalled a dream, ingested the capsules and stayed out of bed for at least 30 minutes. Participants then returned to bed and practiced the Mnemonic Induction of Lucid Dreams technique while returning to sleep. The percentage of participants who reported a lucid dream was significantly increased for both 4 mg (27%, odds ratio = 2.29) and 8 mg doses (42%, odds ratio = 4.46) compared to the active placebo procedure (14%). Galantamine also significantly increased dream recall, sensory vividness and complexity (p<0.05). Dream recall, cognitive clarity, control, positive emotion, vividness and self-reflection were increased during lucid compared to non-lucid dreams (p<0.0001). These results show that galantamine increases the frequency of lucid dreams in a dose-related manner. Furthermore, the integrated method of taking galantamine in the last third of the night with at least 30 minutes of sleep interruption and with an appropriately focused mental set is one of the most effective methods for inducing lucid dreams available today.
Highlights
During a lucid dream one becomes aware that one is dreaming while continuing to dream
The double blind and placebo-controlled design of this study provides strong evidence that cholinergic enhancement with galantamine causally increases the frequency of lucid dreams in a dose-related manner
Increased incidence of lucid dreaming was observed for both 4 mg (27%) and 8 mg (42%) doses compared to 14% for the active placebo, with an increased incidence of lucid dreams in the 8 mg dose compared to 4 mg dose
Summary
During a lucid dream one becomes aware that one is dreaming while continuing to dream. Follow-up studies have confirmed that MILD can increase lucid dream frequency [15] Another lucid dream induction technique is to use a sensory stimulus as a cue, such as a flashing light applied over the sleeper’s eyes via a sleep mask during REM sleep [8, 10]. Subsequent studies showed that combining MILD with a longer period of wakefulness of either 30 to 60 minutes late in the sleep cycle was associated with even higher increases in lucid dream frequency in the ensuing sleep period [18]. We tested the effect of galantamine taken during a period of sleep interruption after approximately the third REM cycle This design allowed us to examine the combined effectiveness of an integrated lucid dream induction protocol, incorporating sleep interruption and the MILD technique together with cholinergic enhancement. Data was collected using a double blind, placebo-controlled, cross-over design across six lucid dreaming training programs
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
