Abstract
Rat dams were fed diets containing either 8 or 25 per cent protein during lactation. Owing to a 1-day difference in molar eruption, pups were killed on either day 17 or 18. The first and second maxillary molars were dissected out and were acid-treated in a sealed plastic chamber through which 10 mM acetic acid (pH 4.5) flowed at a constant rate. Fractional collections were made over 1 h and analysis of Ca, P and F made to evaluate acid solubility. Mineral dissolution in the 8 per cent group, compared to the 25 per cent protein group, was increased in the following proportions: Ca 25.5 per cent, P: 17.'6 per cent, F: 5.8 per cent. The enamel dissolved from molars of rats in the 8 per cent protein group showed a high Ca:P ratio. The increase in acid solubility due to differences in chemical composition of the outer enamel surface may contribute to the increase in caries susceptibility associated with protein-energy malnutrition.
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