Abstract
Pre-Engraftment Syndrome after cord blood transplantation (CBT) is poorly characterized. Therefore, we conducted a review of 52 double unit CBT recipients treated for high-risk hematological malignancies to determine the incidence, manifestations, and outcomes of PES. PES was defined as unexplained fever >38.3ºC (101ºF) unresponsive to antibiotics and/or unexplained skin rash resembling aGVHD occurring prior to or at neutrophil recovery. CBT recipients [median 38 years (range 3–66)] received either ablative (n = 36) or non-myeloablative (NMA, n = 16) conditioning and CSA/MMF.
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