Abstract
PurposeTo evaluate the dosimetry of a six-channel high-dose-rate (HDR) applicator for treatment of esophageal cancer with respect to lateral directionality and heterogeneous media.Material and methodsA computed tomography (CT)- and magnetic resonance imaging (MRI)-compatible esophageal applicator consisting of 2 inflatable portions (anchor and therapeutic balloons) with 6 longitudinal treatment catheters equally spaced circumferentially was constructed. Treatment plans were prepared using Oncentra 4.5 for various catheter loadings and target locations and sizes. Calculated dose distributions were compared to measured distributions obtained using film and a water phantom. Balloon inflations with water and with air were tested.ResultsTG-43 dose calculations matched measurements well when inflation balloons were filled with water. When air was used to inflate, model-based dose calculations (TG-186) improved the comparison with measurement. Several cases with simulated ring targets demonstrated better dose conformity to non-uniform targets compared to a single central catheter. Additionally, the use of this applicator compared to a single catheter, gave rise to considerable improvement in sparing non-target tissue.ConclusionsLateral dose modulation is achievable with the applicator described in this work. The use of TG-186 dose calculation made a small improvement in heterogeneous media.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
