Abstract
ABSTRACT Background : Obese patients with gastroesophageal reflux disease with pathological pH monitoring result may benefit from surgical treatment which is based on the fundoplication technique in association with laparoscopic gastric plication. The Nissen surgery is the gold standard for surgical treatment of gastroesophageal reflux disease, whereas laparoscopic gastric plication is a restrictive surgery that consists of the invagination of the greater curvature, resulting in weight loss. Aim: To compare pre and postoperative pHmetry results and to evaluate weight loss in patients submitted to gastroplasty with fundoplication. Method: Sixteen patients with class I body mass index with symptoms of gastroesophageal reflux with changes of stomach pH and/or erosive esophagitis seen in endoscopy were selected The evaluation of the weight and 24-h pH monitoring was performed preoperatively and postoperatively. The weight, body mass index, percentage of excess weight loss and DeMeester score of patients that underwent the surgery were evaluated pre and postoperatively. Results: Regarding pH monitoring, the average preoperative DeMeester index was 28.7, which was followed by a significant postoperative average reduction to 2.8 (p<0,001). Regarding the weight reduction, the average of weight loss was 13.6 kg and body mass index of 5.3 kg/m2 (p<0.001). Furthermore, the average percentage of excess weight loss was 53.9% (standard deviation=26.2). Conclusion: The combination of Nissen surgery and gastric plication is a viable procedure and appears to be an acceptable option for the treatment of gastroesophageal reflux disease in obese patients, especially patients with obesity class I.
Highlights
Obesity is a chronic disease with a complex and multifactorial etiology, which is characterized by an accumulation of lipids, resulting in metabolic changes
The World Health Organization (WHO) classifies obesity according to body mass index (BMI) in grade I obesity (BMI 30 to 34.9 kg/m2), grade II (35 to 39.9 kg/m2) and grade III (≥40 kg/m2)
The gastroesophageal reflux disease (GERD), which is often related to overweight and obesity comorbidity, is a chronic condition characterized by a retrograde flow of gastric contents and/or duodenal in the absence
Summary
Obesity is a chronic disease with a complex and multifactorial etiology, which is characterized by an accumulation of lipids, resulting in metabolic changes. Obesity is associated with an increased incidence of cardiovascular, neoplastic, gastrointestinal and respiratory diseases[1,4]. According to the Brazilian Institute of Geography and Statistics (BIGS 2008-2009), 49% of the Brazilian adult population is overweight, and 14.8% are obese[14]. Because of the chronic nature of obesity, its treatment is complex and multidisciplinary, which involves changes in lifestyle, and pharmacological and surgical treatment[1]. The gastroesophageal reflux disease (GERD), which is often related to overweight and obesity comorbidity, is a chronic condition characterized by a retrograde flow of gastric contents (hydrochloric acid) and/or duodenal (bile salts and pancreatic enzymes) in the absence
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
